ISO 22400 defines key performance indicators (KPIs) used in manufacturing operations management.

ISO 22400-2:2014 specifies a selected number of KPIs in current practice. The KPIs are presented by means of their formula and corresponding elements, their time behaviour, their unit/dimension and other characteristics. ISO 22400-2:2014 also indicates the user group where the KPIs are used, and the production methodology to which they correspond.

With reference to equipment, the KPIs in ISO 22400-2:2014 relate to work units, as specified in IEC 62264.